Professur für Anorganische Chemie und Umweltchemie

Aktuelles: Forschung

Drug delivery

Antitumor potential of cisplatin loaded into SBA-15 mesoporous silica nanoparticles against B16F1 melanoma cells: in vitro and in vivo studies

D. Drača, D. Edeler, M. Saoud, B. Dojčinović, D. Dunđerović, G. Đmura, D. Maksimović-Ivanić, S. Mijatović, G. N.Kaluđerović

J. Inorg. Biochem. 2021, 217, 111383

Prof. Dr. Dr. Goran Kaluderovic
Professur für Anorganische Chemie und Umweltchemie
Raum: Hg/D/1/08
Telefon: +49 3461 46-2012


      Hochschule Merseburg
      Fachbereich Ingenieur-
      und Naturwissenschaften
      Prof. Dr. Goran Kaluđerović
      Eberhard-Leibnitz-Str. 2
      06217 Merseburg

Special Issue "Organometallic Compounds: Synthesis and Biological Activity"

Dear Colleagues,

Organometallic compounds are important as homogeneous catalysts for the production of pharmaceuticals, among many other products. However, since the reports of the first organometallic chemotherapeutic agent, salvarsan, by Paul Ehrlich (1854–1915, Nobel Prize in Physiology or Medicine in 1908), it has been realized that they can also play an important role as biologically active compounds in the design of novel pharmaceuticals. While only a few organometallic complexes that contain at least one direct metal-carbon bond occur in nature, such as vitamin B12 and some iron and nickel hydrogenases, many organometallic complexes have been studied for biological and medicinal applications. This Special Issue will collect the most recent contributions on the synthesis and biological activities of organometallic complexes in the treatment of viral, fungal, bacterial, and parasitic infections, as well as in the diagnosis and treatment of cancer (also as theranostics), as NO- or CO-releasing molecules, radiopharmaceuticals or for bioanalytical applications.

Prof. Dr. Evamarie Hey-Hawkins
Guest Editor

Institute of Inorganic Chemistry, Leipzig University, Johannisallee 29, D-04103 Leipzig, Germany
Interests: inorganic chemistry; (chiral, functionalised) phosphorus compounds; carboranes; homogeneous catalysis with mono- and multinuclear transition metal complexes; biological and medicinal chemistry with inorganic compounds

Prof. Dr. Santiago Gómez-Ruiz
Guest Editor

Department of Biology, Geology, Physics and Inorganic Chemistry, Universidad Rey Juan Carlos, Mostoles, Spain
Interests: nanomaterials; catalysis; photocatalysis; anticancer; metallodrugs

Prof. Dr. Goran Kaluđerović
Guest Editor

Department of Engineering and Natural Sciences, University of Applied Sciences Merseburg, Eberhard-Leibnitz-Strasse 2, 06217 Merseburg, Germany
Interests: inorganic nanoparticles; cancer treatment; cancer diagnostics; drug delivery systems; cancer targeting

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

  • Antitumour agents
  • Antimicrobial agents 
  • CO-releasing molecules
  • NO-releasing molecules
  • Radiopharmaceuticals
  • Bioanalytics
  • Theranostics





Die Schülergruppe mit Frau Silke Bernhardt (Lehrerin) aus Georg-Cantor-Gymnasium bei uns zu Besuch


Was ist Chemisches Allerlei?

Wenn es dampft, knallt und brennt, Pflanzen unter Wasser wachsen, Geister aus Flaschen entweichen, Herzen bluten und hinter all dem eine chemische Formel steckt!

Das war die Schauvorlesung am 11. September 2019.

Aktuelles: Lehre

Auf Exkursion

Im Rahmen der Module:
Biologische Chemie
Ökologische Stoffwandlung
fand am 13.6.19 eine Exkursion für Studierende im 6. Semester des Studienganges Chemietechnik und am 14.6.19 für den Studiengang Umwelttechnik zum Leibniz-Institut für Pflanzenbiochemie in Halle statt.




Die Schülergruppe aus Georg-Cantor-Gymnasium bei uns zu Besuch


AG Kaluđerović

Ivana Predarska hat die zweite Promotionsstelle im Rahmen des Projekts FEMPOWER an der Hochschule Merseburg erhalten. In ihrem Promotionsvorhaben beschäftigt sich Ivana Predarska mit „Development of novel dual-acting antitumor agents“.

Aktuelles: Forschung

Highly active compounds

The synthetic tubulysin derivative, tubugi-1, improves the innate immune response by macrophage polarization in addition to its direct cytotoxic effects in a murine melanoma model

Dijana Drača, Sanja Mijatović, Tamara Krajnović, Jelena Bogdanović Pristov, Tatjana Đukić, Goran N. Kaluđerović, Ludger A. Wessjohann and Danijela Maksimović-Ivanić

Exp. Cell Res. 2019, in press

Highly active compounds

In vitro anticancer evaluation of novel triphenyltin(IV) compounds with some N-acetyl-S-(naphthoquinone)cysteine derivatives

Nebojša Pantelić, Martina Lerbs, Katharina Wolf, Ludger Wessjohann, Goran N Kaluđerović

J. Serb. Chem. Soc. 2019, in press

Natural compounds

The hop-derived prenylflavonoid isoxanthohumol inhibits the formation of lung metastasis in B16-F10 murine melanoma model

Tamara Krajnović, Dijana Drača, Goran N. Kaluđerović, Duško Dunđerović, Ivana Mirkov, Ludger A. Wessjohann, Danijela Maksimović-Ivanić and Sanja Mijatović

Food Chem. Toxicol. 2019, in press

Mesoporous silica

Impact of the mesoporous silica SBA-15 functionalization on the mode of action of Ph3Sn(CH2)6OH

David Edeler, Dijana Drača, Vladana Petković, Filipe Natalio, Danijela Maksimović-Ivanić, Sanja Mijatović, Harry Schmidt and Goran N. Kaluđerović*

Mat. Sci. Eng. C 2019, 100, 315

Mesoporous silica

The interaction between SBA-15 derivative loaded with Ph3Sn(CH2)6OH and human melanoma A375 cell line: uptake and stem phenotype loss

Danijela Maksimović-Ivanić, Mirna Bulatović, David Edeler, Christian Bensing, Igor Golić, Aleksandra Korać, Goran N. Kaluđerović*, Sanja Mijatović*

J. Biol. Inorg. Chem. 2019, 24, 223


Chlorambucil Conjugated Ugi Dendrimers with PAMAM-NH2 Core and Evaluation of Their Anticancer Activity

Nalin Seixas, Bruno B. Ravanello, Ibrahim Morgan, Goran N. Kaluđerović and Ludger A. Wessjohann

Pharmaceutics 2019, 11, 59

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