Special Issue "Organometallic Compounds: Synthesis and Biological Activity"
Organometallic compounds are important as homogeneous catalysts for the production of pharmaceuticals, among many other products. However, since the reports of the first organometallic chemotherapeutic agent, salvarsan, by Paul Ehrlich (1854–1915, Nobel Prize in Physiology or Medicine in 1908), it has been realized that they can also play an important role as biologically active compounds in the design of novel pharmaceuticals. While only a few organometallic complexes that contain at least one direct metal-carbon bond occur in nature, such as vitamin B12 and some iron and nickel hydrogenases, many organometallic complexes have been studied for biological and medicinal applications. This Special Issue will collect the most recent contributions on the synthesis and biological activities of organometallic complexes in the treatment of viral, fungal, bacterial, and parasitic infections, as well as in the diagnosis and treatment of cancer (also as theranostics), as NO- or CO-releasing molecules, radiopharmaceuticals or for bioanalytical applications.
Prof. Dr. Evamarie Hey-Hawkins
Institute of Inorganic Chemistry, Leipzig University, Johannisallee 29, D-04103 Leipzig, Germany
Interests: inorganic chemistry; (chiral, functionalised) phosphorus compounds; carboranes; homogeneous catalysis with mono- and multinuclear transition metal complexes; biological and medicinal chemistry with inorganic compounds
Prof. Dr. Santiago Gómez-Ruiz
Department of Biology, Geology, Physics and Inorganic Chemistry, Universidad Rey Juan Carlos, Mostoles, Spain
Interests: nanomaterials; catalysis; photocatalysis; anticancer; metallodrugs
Prof. Dr. Goran Kaluđerović
Department of Engineering and Natural Sciences, University of Applied Sciences Merseburg, Eberhard-Leibnitz-Strasse 2, 06217 Merseburg, Germany
Interests: inorganic nanoparticles; cancer treatment; cancer diagnostics; drug delivery systems; cancer targeting
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Antitumour agents
- Antimicrobial agents
- CO-releasing molecules
- NO-releasing molecules
Was ist Chemisches Allerlei?
Wenn es dampft, knallt und brennt, Pflanzen unter Wasser wachsen, Geister aus Flaschen entweichen, Herzen bluten und hinter all dem eine chemische Formel steckt!
Das war die Schauvorlesung am 11. September 2019.
Im Rahmen der Module:
fand am 13.6.19 eine Exkursion für Studierende im 6. Semester des Studienganges Chemietechnik und am 14.6.19 für den Studiengang Umwelttechnik zum Leibniz-Institut für Pflanzenbiochemie in Halle statt.
Ivana Predarska hat die zweite Promotionsstelle im Rahmen des Projekts FEMPOWER an der Hochschule Merseburg erhalten. In ihrem Promotionsvorhaben beschäftigt sich Ivana Predarska mit „Development of novel dual-acting antitumor agents“.
Highly active compounds
Dijana Drača, Sanja Mijatović, Tamara Krajnović, Jelena Bogdanović Pristov, Tatjana Đukić, Goran N. Kaluđerović, Ludger A. Wessjohann and Danijela Maksimović-Ivanić
Exp. Cell Res. 2019, in press
Highly active compounds
Nebojša Pantelić, Martina Lerbs, Katharina Wolf, Ludger Wessjohann, Goran N Kaluđerović
J. Serb. Chem. Soc. 2019, in press
Tamara Krajnović, Dijana Drača, Goran N. Kaluđerović, Duško Dunđerović, Ivana Mirkov, Ludger A. Wessjohann, Danijela Maksimović-Ivanić and Sanja Mijatović
Food Chem. Toxicol. 2019, in press
David Edeler, Dijana Drača, Vladana Petković, Filipe Natalio, Danijela Maksimović-Ivanić, Sanja Mijatović, Harry Schmidt and Goran N. Kaluđerović*
Mat. Sci. Eng. C 2019, 100, 315
Danijela Maksimović-Ivanić, Mirna Bulatović, David Edeler, Christian Bensing, Igor Golić, Aleksandra Korać, Goran N. Kaluđerović*, Sanja Mijatović*
J. Biol. Inorg. Chem. 2019, 24, 223
Nalin Seixas, Bruno B. Ravanello, Ibrahim Morgan, Goran N. Kaluđerović and Ludger A. Wessjohann
Pharmaceutics 2019, 11, 59